Andrea usually says something relevant.
In Poul Anderson's Genesis, a far future post-organic intelligence creates simulated environments with conscious inhabitants who think that they really are living in ancient Greece, in nineteenth century England or in an alternative history etc. Andrea summarizes current arguments to the conclusion that we are now living in such a simulation.
(i) If there is one material environment containing many simulated environments, including simulations within simulations, then it is statistically more probable that we are living in one of the simulations than in the original material environment.
(ii) Apparently, sub-atomic particles are observed to exhibit properties that would conform to the simulation theory but I have lost track of the argument.
See:
It gets complicated - and it is getting late here. But Anderson's sf is still at the forefront of speculation.